Under the patronage of Prof. Mohamed Diaa Zain El-Abedeen, President of Ain Shams University, the university has achieved an accomplishment in its international rankings portfolio. The QS World University Rankings announced the results of its 2025 edition for university specializations. The university appeared in the five basic sciences of the ranking, appearing for the first time in the humanities specialization, in addition to appearing in 15 sub-specializations, namely:

 Engineering and Technology: Ain Shams University is ranked 267

 Computer Science and Information Systems: Ain Shams University is ranked 351–400

 Electrical and Electronics Engineering: Ain Shams University is ranked 201–250

 Mechanical Engineering: Ain Shams University is ranked 301–350

 Chemical Engineering: Ain Shams University is ranked 351–400

 Civil Engineering: Ain Shams University is ranked 201–275

 Life Sciences and Medicine: Ain Shams University is ranked 315

 Agriculture: Ain Shams University is ranked 251–300

 Biological Sciences: Ain Shams University is ranked 351–400

 Medicine: Ain Shams University is ranked 251–300

 Pharmacy: Ain Shams University is ranked 315 151–200

 Natural Sciences: Ain Shams University is listed in the 401–450 category

Chemistry: Ain Shams University is listed in the 301–350 category

 Environmental Sciences: Ain Shams University is listed in the 401–450 category

 Mathematics: Ain Shams University is listed in the 401–450 category

 Materials Sciences: Ain Shams University is listed in the 451–500 category for Physics and Astronomy

 Arts and Humanities: Ain Shams University is listed in the 501–550 category

Architecture: Ain Shams University is listed in the 201–260 category

 Social and Administrative Sciences: Ain Shams University is listed in the 501–550 category