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Animal research plays an important role in our understanding of health and disease and in the development of modern medicines and surgical techniques. Without the use of animals, we would not have many of the modern medicines, antibiotics, vaccines and surgical techniques that we take for granted in both human and veterinary medicine.
Animal research remains a small but vital part of the quest for new medicines, vaccines and treatments for humans and animals. Alternative methods are gradually being phased in, but, until we have sufficient reliable alternatives available, it is important that organizations that use animals in research maintain the public’s trust in them. By providing this level of information about the numbers of animals used, and the experience of those animals, as well as details of the medical breakthroughs that derive from this research
About Us
Vision
To be a pioneer and a model center in providing quality laboratory animal care , and excellent services to support biomedical research
Objectives
* Construct a state of the art newly designed building with a controlled environment to assure the standard humane care and well-being of the animals
* Implement a comprehensive animal care that follow the international guideline Ethical Conduct in the Care and Use of Animals in Research
* Breed special animal strains specially those used for induction of cancer and chronic inflammatory diseases
* Collaborate with the other internal units to create our own projects
* Conduct different animal researches with high impact value
Provided services:
* Provides laboratory animals breeding facilities.
* Housing mice, rats, hamsters and rabbits for many researchers in different faculties.
* Many services are conducted by the unit for example; Introduction of medicines by different route to the animals to treat infectious and non-infectious diseases, observing and caring for animals during the experiment, taking different required samples either blood or tissue
* Surgical intervention is performed in a well-equipped theater by a qualified vet, on various species of small animals, such as albino mice, albino rats, New Zealand and Indian rabbits. The guidelines of ethics for scientific research are followed as regards the use of anesthetics in specific doses and animal care with analgesics and various antibiotics whether it is local or general
* Conduct Pharmacokinetic and Pharmacodynamics studies in different animal species.
* Conduct Safety and Toxicity studies for new drug molecules.
* Induce different animal models of diseases.
* Workshops were conducted for training of medical students on all types of animal injection methods and how- to take blood and tissue samples
Infrastructure (photos)
• 4 animal holding rooms
• 1 procedure room
• 1 operations room
*All rooms are air conditioned and well ventilated
Stakeholders
1- Vaccera
2- Desert Research Center
3- Medical Ain shams Research Institute - MASRI
* Bio bank
* Molecular and Genomics Unit
* Tissue Culture and Stem Cell Unit
4- National Cancer Institute
5- National Center for Social and Criminological Research
6- Libya - Faculty of medicine
7- Faculty of medicine army
8- Ain-Shams University
* Faculty of Medicine (Forensic department - Histology department - The Clinical Oncology - anatomy department)
* Faculty of Dentistry
* Faculty of pharmacology
* Faculty of Women`s college
* Faculty of Science
9- Cairo University
* Faculty of Medicine
* Faculty of Veterinary Medicine
10- Helwan University
* Faculty of Medicine
* Faculty of Science
* Faculty of Home economics
11- Monofiya University
* Faculty of Home economics
12- BUC University
* Faculty of dentistry
13- CIC
14- BUE University
* Faculty of Medicine
* Faculty of Dentistry
15- Zagazig University
* Faculty of veterinary Zagazig university cooperation with berlin university
* Faculty of Home economics
16- Al-Azhar University
* Faculty of Dentistry
* Faculty of Home economics
17-Ismallia University
* Faculty of Dentistry
18-Suze canal University
* Faculty of Medicine
19-Beni suef University
* Faculty of Medicine
20-MSA University
21- Sina University
* Faculty of Science
22-Mansoura University
* Faculty of Dentistry
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DIRECTOR : Prof.Hala El-Wakil, MD Dr Elwakil is the associate editor of Parasitologists United Journal ( PUJ) . She is a member of the scientific committees for the promotion of professors and associate professors of medical parasitology from 2019-2022 . Between 2012-2018 She was the director of Parasitological Research & Diagnostic Unit, Faculty of medicine ASU. She is an active board member and the treasurer of Egyptian parasitologist united EPU society and a member of the Asian Council of Science Editors ACSE's.
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Deputy director : Ahmed Mohamed Mukhtar, D.V.M. Mukhtar has worked at Police Heights Equine Hospital as a consultant and Lecturer “Department of Obstetrics and Gynecology”2021 - 2022 , laboratory with an ISO certificate in the scope of Veterinary Tests at LeptoVet Lab, supervisor of Diagnostic Imaging and Endoscopy Unit, at Agricultural Research Center - Animal Reproduction Research institute 2020 - 2021, Supervisor of the facilitation and development of the Equestrian School at The Egyptian Agricultural Organization EAO - Al Zahraa Stud for Arabian Horses Breeding 2018 – 2021 Mukhtar got internship German (2020), trained at Haupt- und Landgestüt Marbach - March 2020, the training program on dealing with Insemination station (Offenhausen stud yard) stallions ‘management, semen processing etc , Breeding station, Natural mating and insemination for external mares, Embryo transfer (Offenhausen stud yard) Mares and (Marbach stud yard): foal barn (Marbach): Fertility, management, birth management, herd management, Rearing: herd management, basic education for foals (vaccination, deworming) Attended internship in Tierärztliches Zentrum für Pferde in Kirchheim (March 2020) for training on emergency medicine cases in hospital and musculoskeletal diagnosis and many surgical operation
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Deputy director: Ahmed Osama Hegazy, D.V.M. Hegazy has worked at Equine & Pet Hospital as a vet surgeon; He was responsible for explanation to students How to secure and start the examination, Veterinary care, Treatment, Diagnostic Radiology (X-Ray, Ultrasound), (Estrous, Pregnancy and Fertility Problems), Embryo Flush and Transfer Endoscopy Hegazy has worked as an Auditor and consultant (QHSE) Food safety, Occupational safety and health, He has Courses on GMPs, HACCP System, ISO 2200, Awareness and internal Audit (2019). Hegazy has Diploma in Biochemistry from Beni Suief University (2019-2020), Diploma in Small Animal Surgery (2022-2023) from Assuite University. Hegazy was an active Member at Arab Equine Veterinary Association (2022) |
Research and publications
1- Immune-Modulatory Changes After Transplantation Therapy of Insulin Producing Cells Derived from Wharton’s Jelly Human Umbilical Cord- Mesenchymal Stem Cells in Diabetes Induced Rats
Omayma M Hassanin , Tarek M El-Masry , Fatma A Abu-Zahra , Sawsan El-Adawy , Ahmed M Abdellah . Egypt J Immunol. 2019 Jan;26(1):55-67.
2- Effect of Bone Marrow-Derived Mesenchymal Stem Cells on Ischaemic- Reperfused Hearts in Adult Rats with Established Chronic Kidney Disease.
Gehane M Hamed 1, Wessam E Morsy 1, Manal S Abd-El Hamid 1, Arwa Abd El Moniem Hassan 1, Fatma A Abu Zahra. Int J Stem Cells . 2019 Jul 31;12(2):304-314. doi: 10.15283/ijsc18114.
3- A Clinicopathological Study Comparing the Therapeutic Role of the Mesenchymal Stem Cell and Bevacizumab as Anti Vascular Endothelial Growth Factor on the Lung as an Extra-articular Target in Adjuvant Induced Arthritis in Rats
Fatma A. Zahra. Stem Cell January 2019 DOI: 10.7537/marsscj100119.03
4- Bone marrow derived-mesenchymal stem cells downregulate IL17A dependent IL6/STAT3 signaling pathway in CCl4-induced rat liver fibrosis
Shimaa Farouk , Salwa Sabet , Fatma A Abu Zahra , Akmal A El-Ghor , PLoS One . 2018 Oct 22;13(10):e0206130.
5- In vitro comparative study between mechanically emulsified fat grafts and enzymatically emulsified fat grafts.
Raghda Fayek Shaker , Abdel Rahman M Abdel Aal , Khaled Mohamed Ali El Gazzar , Fatma Abdel Karim Abu Zahra , Ahmed Elshahat , Eplasty . 2020 Apr 17:20:e1. eCollection 2020.
6- The optimal timing of adipose derived stem cells injection to improve skin flap survival in a rat model
Ahmed Atef, Ayman Abu El Makarem Shaker, Eman Yahya Sadek, Nahed Samir Boughdadi, Suzi Sobhy Atalla & Fatma Abu Zahra, European Journal of Plastic Surgery August 2018
7- Ameliorative role of bone marrow mesenchymal stem cells and rutin against acetaminophen induced hepatotoxicity in adult male rats
Walaa A. M. El-Nahrawy , Fatma A. Abu Zahra and Rabha E. A. EL-Dab, International Journal of Advanced Research (IJAR , Sept 2017
8- Bone Marrow-Derived Mesenchymal Stem Cell Potential Regression of Dysplasia Associating Experimental Liver Fibrosis in Albino Rats
Yasmine H. Khalifa, Ghada M. Mourad, Wahid M. Stephanos, Sahar A. Omar, and Radwa A. Mehanna , Biomed Res Int. 2019; 2019: 5376165.
9- Estimation of postmortem intervals through analysis of biochemical and histomorphological alteration in blood uterus prostate and lung of drowned rats with or without clozapine intake
Amr R Zaki , Adel F Tohamy , Nour El-houda Yaseen , Mansoura Journal of forensic medicine and clinical toxicology January 2017